0742 Is sleep altered during the menstrual cycle? A polysomnography study from EPISONO

Abstract Introduction During the reproductive life, woman experiences changes in their hormone levels that characterize her menstrual cycle. This monthly event provides hormonal and body conditions to development of pregnancy lactation. In addition alterations hormones, some women present physical psychological complaints according phase Sleep has been reported be deteriorated during menses; however, no conclusive results have stated. The aim our study was evaluate objective subjective sleep 3 different time-points Methods For this we used São Paulo Epidemiological Study (EPISONO) database. Ninety-one were distributed follicular (F) (N=27), luteal (L) (N=39) menstruation (M, N=25) undergone a one-night polysomnography. Blood samples women’s questionnaire data collected investigate information about cycle identify polysomnography exam. parameters analyzed were: efficiency, latency, REM total time, awakenings index, percentage stage 1, 2, N3 sleep. following questionnaires applied assess sleep: Pittsburgh Quality Index, Insomnia Severity Chalder Fatigue Scale, Beck Anxiety Inventory, Depression Inventory Epworth Sleepiness Scale. statistical analysis Kruskal-Wallis test post-hoc Dunn, with p< 0.05. Results Women exhibited significantly higher efficiency (89.9±9.6%) when compared (83.7±12.7%; p=0.02) (83±10.8%; p=0.008) groups. latency statistically reduced (7.1min) other (L=15.9min; M=22.3min; p=0.02; p=0.03, respectively). did not differences Conclusion showed better than times longer phase, indicating may one causes women. Support (if any) AFIP CNPq.